Cre-LoxP Recombination
Theadv...
The advent of tamoxifen (Tm)-inducible Cre recombinases has greatly improved the ability to temporally control Cre-loxP recombination in vivo, ...,The Cre/lox site-specific recombination system has emerged as an important tool ... Cre recombinases that can be activated by administration of tamoxifen to the ... , Temporal genetic modification of mice using the ligand-inducible Cre/loxP system is an important technique that allows the bypass of ..., For tamoxifen-dependent Cre recombinase, also known as CreER recombinase, tamoxifen (TAM) is used to activate the Cre to generate time- ..., This causes nuclear translocation of CreERT and the interaction of Cre with loxP sites (Figure 2A). In this system, tamoxifen is systemically ...,Cre-Lox recombination is a site-specific recombinase technology, used to carry out deletions, ..... Once tamoxifen is introduced, the mutated recombinase is shuttled back into the nucleus and is able to cleave the lox sites, resulting in a loss of .....
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The advent of tamoxifen (Tm)-inducible Cre recombinases has greatly improved the ability to temporally control Cre-loxP recombination in vivo, ...,The Cre/lox site-specific recombination system has emerged as an important tool ... Cre recombinases that can be activated by administration of tamoxifen to the ... , Temporal genetic modification of mice using the ligand-inducible Cre/loxP system is an important technique that allows the bypass of ..., For tamoxifen-dependent Cre recombinase, also known as CreER recombinase, tamoxifen (TAM) is used to activate the Cre to generate time- ..., This causes nuclear translocation of CreERT and the interaction of Cre with loxP sites (Figure 2A). In this system, tamoxifen is systemically ...,Cre-Lox recombination is a site-specific recombinase technology, used to carry out deletions, ..... Once tamoxifen is introduced, the mutated recombinase is shuttled back into the nucleus and is able to cleave the lox sites, resulting in a loss of .....
#1 Tamoxifen-Induced Cre-loxP Recombination Is ...
The advent of tamoxifen (Tm)-inducible Cre recombinases has greatly improved the ability to temporally control Cre-loxP recombination in vivo, ...
The advent of tamoxifen (Tm)-inducible Cre recombinases has greatly improved the ability to temporally control Cre-loxP recombination in vivo, ...
#2 Inducible Cre mice.
The Cre/lox site-specific recombination system has emerged as an important tool ... Cre recombinases that can be activated by administration of tamoxifen to the ...
The Cre/lox site-specific recombination system has emerged as an important tool ... Cre recombinases that can be activated by administration of tamoxifen to the ...
#3 Establishment of a tamoxifen
Temporal genetic modification of mice using the ligand-inducible Cre/loxP system is an important technique that allows the bypass of ...
Temporal genetic modification of mice using the ligand-inducible Cre/loxP system is an important technique that allows the bypass of ...
#4 Optimizing tamoxifen
For tamoxifen-dependent Cre recombinase, also known as CreER recombinase, tamoxifen (TAM) is used to activate the Cre to generate time- ...
For tamoxifen-dependent Cre recombinase, also known as CreER recombinase, tamoxifen (TAM) is used to activate the Cre to generate time- ...
#5 Mouse Cre
This causes nuclear translocation of CreERT and the interaction of Cre with loxP sites (Figure 2A). In this system, tamoxifen is systemically ...
This causes nuclear translocation of CreERT and the interaction of Cre with loxP sites (Figure 2A). In this system, tamoxifen is systemically ...
#6 Cre
Cre-Lox recombination is a site-specific recombinase technology, used to carry out deletions, ..... Once tamoxifen is introduced, the mutated recombinase is shuttled back into the nucleus and is able to cleave the lox sites, resulting in a loss of ..
Cre-Lox recombination is a site-specific recombinase technology, used to carry out deletions, ..... Once tamoxifen is introduced, the mutated recombinase is shuttled back into the nucleus and is able to cleave the lox sites, resulting in a loss of ..
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為了研發新藥或是新式手術,實驗人員經常會以老鼠為研究對象。國科會國家實驗中心建立全球第一個設計生產「可調控基因轉殖大鼠」的技術平台,能夠依照研究需求,製造多種人類疾病模式的大鼠,在基因轉殖技術...
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